Strategies and Technologies to Combat Antibiotic Resistance - Agenda
Day One • Wednesday, April 6
8:30 am Welcome Remarks
Carrie Harwood PhD. • University of Washington School of Medicine
8:45 am Keynote Speaker
Ada Yonath, PhD. • Weizmann Institute of Science
Next Generation Antibiotics
9:30 am SESSION I • New Approaches to Diagnosis of AMR
Speaker Presentations and Discussion
9:30 am Deborah Hung, MD, PhD. • Broad Institute and Harvard Medical School
Genomics, Antibiotic Resistance and Diagnostics
10:15 am Morning Break
10:45 am Uri Gophna, PhD. • Tel Aviv University
Antibiotic Resistance in the Gut - Lessons From Metagenomics
11:30 am SESSION II • Phenotypic Resistance to Antibiotics
Speaker Presentations and Discussion
11:30 am Mark P. Brynildsen, PhD. • Princeton University
Toward Knowing Thy Enemy: Investigations of Bacterial
Persister Physiology
12:15 pm Sophie Helaine, PhD. • Harvard Medical School
Salmonella Persistence During Infection: Trade-off Between Mitigating DNA Damage and Ability to Relapse
2:00 pm Carl F. Nathan, MD. • Weill Cornell Medicine
Cryptic Phenotypic Resistance: “Differentially Detectable” Bacteria
2:45 pm Nathalie Balaban, PhD. • The Hebrew Universityof Jerusalem
The Impact of the Disrupted Cellular State on Drug Response
4:00 pm James J. Collins, PhD. • Massachusetts Institute of Technology
Harnessing Deep Learning for Antibiotic Discovery
4:45 pm Day 1 Roundup
7:15 pm Keynote Speaker
Martin J. Blaser, MD. • Rutgers University
Antibiotic Resistance Is the Tip of the Iceberg of Ecological Change
8:00 pm Bus from NAS Building to Fairmont Hotel
Day Two • Thursday, April 7
7:30 am First Bus from Fairmont Hotel to NAS Building
7:45 am Breakfast
8:00 am Second Bus from Fairmont Hotel to NAS Building
8:30 am SESSION III • Evolutionary Dynamics of AMR
Speaker Presentation and Discussion
8:30 am Michael Baym, PhD. • Harvard Medical School
Non-anthropogenic Selective Pressures on Resistance Evolution
9:15 am Jacob Scott, MD, PhD. • Cleveland Clinic
Using Fitness Seascapes and Counterdiabatic Driving to Enable Control of Evolving Populations of Microbes
10:30 am Roy Kishony, PhD. • Technion–Israel Institute of Technology
Predicting Antibiotic Resistance and Treatment Failure
11:15 am Avigdor Eldar, PhD. • Tel Aviv University
Short-Range Bacterial Communication and Its Implications
1:00 pm SESSION IV • Alternative Approaches to Therapy
Speaker Presentation and Discussion
1:00 pm Roi Avraham, PhD. • Weizmann Institute of Science
Understanding Metabolic Preferences of Bacterial
Pathogens as Novel Metabolotherapies to Infection
1:45 pm Paul Turner, PhD. • Yale University
Phage Therapy to Combat Infections by Antibiotic-Resistant Bacterial Pathogens
3:00 pm Ilan Rosenshine, PhD. • The Hebrew University of Jerusalem
Life on the Surface of Intestinal Epithelium:
The Enteropathogenic E. coli Paradigm
3:45 pm Timor Baasov, PhD. • Technion–Israel Institute of Technology
Towards Catalytic Antibiotics as a New Paradigm in
Antibiotics Research
4:30 pm Rotem Sorek, PhD. • Weizmann Institute of Science
Phages, the Natural Killers of Bacteria
